Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611607 | 0.81 | KDR (0.39) | MMP12MEN1KMT2AKDRBRD4 | |
| SCHEMBL21611552 | 0.76 | MAPT (0.47) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL21611540 | 0.76 | MAPT (0.49) | ALDH1A1MAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL21858751 | 0.74 | MAPT (0.55) | ALDH1A1MAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL21611504 | 0.74 | LMNA (0.50) | ALDH1A1MAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL21611500 | 0.74 | MAPT (0.60) | ALDH1A1MAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL31200193 | 0.73 | MMP12 (0.56) | ALDH1A1MMP12MEN1KMT2AKDR | |
| SCHEMBL12925129 | 0.73 | MMP12 (0.56) | ALDH1A1MMP12MEN1KMT2AKDR | |
| SCHEMBL9165003 | 0.73 | CA1 (0.49) | ALDH1A1MAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL21611534 | 0.72 | MAPT (0.56) | ALDH1A1MAPTLMNASMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818054-A1 | AMINO-PYRIMIDONYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2021-05-12 | — | — | EP | disclosed |
| CN-112368276-A | Amino-pyrimidinone derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-02-12 | — | — | CN | disclosed |
| WO-2020008013-A1 | AMINO-PYRIMIDONYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2020-01-09 | — | — | WO | disclosed |