Phosphoric Acid

Phosphoric Acid

SCHEMBL21612166

C=C(CCCCCC)C(=O)OC(C)O.O=P(O)(O)O

nearest known ligand 0.45

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
ENPP2 Q13822 6/20 0.44
LPAR3 Q9UBY5 4/20 0.44
LPAR1 Q92633 3/20 0.44
LPAR6 P43657 1/20 0.44
LPAR4 Q99677 1/20 0.44
LPAR5 Q9H1C0 1/20 0.44
LPAR2 Q9HBW0 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 1/20 0.41
SMPD1 P17405 3/20 0.40
PLA2G4A P47712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820057 0.94 LMNA (0.50) LMNAMAPT
SCHEMBL16499607 0.94 LMNA (0.50) LMNAMAPT
SCHEMBL27822863 0.87 LMNA (0.40) LMNAMAPT
SCHEMBL15610760 0.82 LMNA (0.61) LMNAMAPT
SCHEMBL29177465 0.82 LMNA (0.61) LMNAMAPT
SCHEMBL11171251 0.82 LMNA (0.61) LMNAMAPT
SCHEMBL29096239 0.82 LMNA (0.61) LMNAMAPT
SCHEMBL29117791 0.80 LMNA (0.58) LMNAMAPT
SCHEMBL5716611 0.79 ALDH1A1 (0.34) LMNAMAPT
SCHEMBL2850275 0.79 LMNA (0.49) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111867682-B Waterproof cosmetic composition 可泰克斯公司 2023-07-07 CN claimed
CN-111867682-B Waterproof cosmetic composition 可泰克斯公司 2023-07-07 CN disclosed
EP-3817708-A1 COSMETIC CLEANSING FORMULATION Coatex (FR) 2021-05-12 EP disclosed
WO-2020008119-A1 COSMETIC CLEANSING FORMULATION COATEX (FR) 2020-01-09 WO disclosed