Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | PPARD | Q03181 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24037921 | 0.75 | ALDH1A1 (0.38) | MEN1KMT2ATRPA1HAO1 | |
| SCHEMBL6032672 | 0.73 | MET (0.52) | MET | |
| SCHEMBL23355336 | 0.73 | KDR (0.38) | — | |
| SCHEMBL2925168 | 0.72 | — | — | |
| SCHEMBL2934749 | 0.71 | MET (0.40) | SCN4ASCN9AMET | |
| SCHEMBL29177399 | 0.71 | EPHX2 (0.45) | MEN1KMT2ASCN8ASCN10AKIF11 | |
| SCHEMBL28116973 | 0.71 | MEN1 (0.38) | SCN4ASCN9AMEN1KMT2APARP10 | |
| SCHEMBL6172318 | 0.69 | CES2 (0.45) | SCN4AMEN1KMT2A | |
| SCHEMBL27777720 | 0.69 | KMT2A (0.47) | MEN1KMT2AKIF11 | |
| SCHEMBL28540608 | 0.69 | KDM4C (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009156-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVE | 第一三共株式会社 | 2020-01-09 | — | — | WO | disclosed |