SCHEMBL216136

SCHEMBL216136

O=S(=O)(O)c1cc(S(=O)(=O)O)cc(S(=O)(=O)O)c1.[Ag]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.55
FYN P06241 1/20 0.55
ING2 Q9H160 1/20 0.52
TSHR P16473 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 1/20 0.48
ALDH1A1 P00352 5/20 0.46
NT5E P21589 3/20 0.46
HSD17B10 Q99714 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
CASP6 P55212 3/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NSD2 O96028 3/20 0.40
GAA P10253 1/20 0.40
PLCG1 P19174 1/20 0.40
DNMT1 P26358 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DUSP3 P51452 1/20 0.39
PTPN5 P54829 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219222 0.96 LCK (0.57) LCKFYNING2TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL23302213 0.93 LCK (0.55) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL9220939 0.93 LCK (0.55) LCKFYNING2TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL9775388 0.93 LCK (0.55) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL5013229 0.93 LCK (0.55) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL124133 0.93 LCK (0.55) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL7803308 0.84 LMNA (0.55) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL7803304 0.84 LCK (0.48) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL11409650 0.82 LCK (0.46) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL9550121 0.82 ALDH1A1 (0.67) LCKFYNTSHRSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
CN-101835735-A Bottom antireflective coating composition AZ ELECTRONIC MATERIALS USA 2010-09-15 CN disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
US-5200544-A Acid generator, acid sensitive polymer; photosensitivity AT&T BELL LABORATORIES (US) 1993-04-06 US disclosed
US-5135838-A Resin sensitive to UV radiation and a nitrobenzyl compound that generates an acid AT&T BELL LABORATORIES (US) 1992-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 LCK 3790/4885FYN 1566/4885ING2 3845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.