Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18201529 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10HPGDEPHX2 | |
| SCHEMBL29893694 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD17B10HPGDSLC6A2 | |
| SCHEMBL29104474 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD17B10HPGDSLC6A2 | |
| SCHEMBL24166422 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HSD17B10HPGDMAPT | |
| SCHEMBL21615033 | 0.82 | PDK2 (0.36) | JAK2 | |
| SCHEMBL23288288 | 0.81 | FABP3 (0.41) | MAPTMAPK10MAPK14KDM4E | |
| SCHEMBL31650930 | 0.81 | FABP3 (0.41) | MAPTMAPK10MAPK14KDM4E | |
| SCHEMBL17760830 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP3A4HSD17B10HPGDEPHX2 | |
| SCHEMBL21665619 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP3A4HSD17B10HPGDEPHX2 | |
| SCHEMBL23697408 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
| WO-2020007770-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MAOB, TYR, INMT | ALDH1A1 777/4885CYP3A4 167/4885HSD17B10 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.