Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19618934 | 0.82 | MAPT (0.47) | HTR2CKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL5717063 | 0.79 | ENPP3 (0.46) | LTA4HSCN9AKMT2AENPP3ENPP1 | |
| SCHEMBL28232336 | 0.77 | SLC6A3 (0.49) | KMT2AHTTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL18295372 | 0.77 | HTT (0.46) | HTR2CKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL29035303 | 0.77 | HTT (0.46) | HTR2CKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL28789042 | 0.77 | HTT (0.46) | LTA4HHTR2CKMT2AHTTSMN1; SMN2 | |
| SCHEMBL27740311 | 0.77 | TDP1 (0.46) | SCN9AHTR2CKMT2AHTTSMN1; SMN2 | |
| SCHEMBL3060268 | 0.77 | HTT (0.46) | HTR2CKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL16197773 | 0.77 | HTT (0.46) | HTR2CKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL23356900 | 0.76 | DPP4 (0.49) | HTR2CKMT2AHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |