Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420969 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| Formic Acid SCHEMBL28572560 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL4967588 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL39118 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL27700719 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL28675532 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL8445150 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL317508 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8612216 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| Potassium SCHEMBL317509 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |