Sugi Predict

Sugi Predict / Compounds / SCHEMBL317508

SCHEMBL317508

SCHEMBL317508

NC(=O)c1ccccc1C(N)=O.[KH]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.67
▸ KDM4E B2RXH2 4/20 0.67
▸ MAPT P10636 3/20 0.67
▸ TSHR P16473 2/20 0.67
▸ HSD17B10 Q99714 2/20 0.67
▸ HPGD P15428 2/20 0.67
▸ METAP2 P50579 1/20 0.61
▸ BCAT2 O15382 1/20 0.58
▸ PARP1 P09874 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ BLM P54132 1/20 0.52
▸ PMP22 Q01453 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ GAA P10253 1/20 0.52
▸ CTNNB1 P35222 1/20 0.52
▸ SIRT1 Q96EB6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27700719 0.97 ALDH1A1 (0.70) ALDH1A1KDM4EMAPTTSHRHSD17B10
SCHEMBL39118 0.97 ALDH1A1 (0.70) ALDH1A1KDM4EMAPTTSHRHSD17B10
SCHEMBL4967588 0.97 ALDH1A1 (0.70) ALDH1A1KDM4EMAPTTSHRHSD17B10
Hydrochloric Acid SCHEMBL8612216 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10
Potassium SCHEMBL30716407 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10
SCHEMBL28458750 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10
SCHEMBL1158413 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10
Potassium SCHEMBL317509 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10
SCHEMBL31285706 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10
SCHEMBL8445150 0.94 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478155-B Preparation method of grapiprant and intermediate thereof 洛阳惠中兽药有限公司 2025-06-13 — — CN claimed
WO-2025107394-A1 PERFLUOROPOLYETHER-MODIFIED SILICON DIOXIDE MATERIAL AND PREPARATION METHOD THEREFOR 中石油(上海)新材料研究院有限公司 2025-05-30 — — WO claimed
CN-120025698-A Perfluoropolyether modified silicon dioxide material and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-05-23 — — CN claimed
CN-119390584-A Preparation of pentazocine method for preparing octyl intermediate 和鼎（南京）医药技术有限公司 2025-02-07 — — CN claimed
CN-117263886-A Preparation method of 2, 5-tetrahydrofuran dimethylamine 中科国生(杭州)科技有限公司 2023-12-22 — — CN claimed
CN-116478155-A Preparation method of grapiprant and intermediate thereof 洛阳惠中兽药有限公司 2023-07-25 — — CN claimed
CN-114230628-A Quinacridone cholesterol compound and preparation method and application thereof 华东理工大学 2022-03-25 — — CN claimed
CN-109438351-B Preparation method of pentazocine intermediate 和鼎（南京）医药技术有限公司 2021-04-23 — — CN claimed
CN-108373419-B 3-branched alkyl chain and preparation method thereof 九江德思光电材料有限公司 2020-12-22 — — CN claimed
WO-2015162622-A1 PROCESS FOR PREPARATION OF LINEZOLID VIRDEV INTERMEDIATES PVT. LTD. (IN) 2015-10-29 — — WO claimed
US-20040006238-A1 Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY 2004-01-08 — — US claimed
US-20030216572-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY 2003-11-20 — — US claimed
US-20030130509-A1 PROCESS TO PRODUCE 3-CARBON AMINO ALCOHOL SALTS PHARMACIA & UPJOHN COMPANY 2003-07-10 — — US claimed
US-20030065219-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY 2003-04-03 — — US claimed
US-20020095054-A1 Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY 2002-07-18 — — US claimed
US-20020032348-A1 Process to produce oxazolidinones PEARLMAN BRUCE ALLEN (US) 2002-03-14 — — US claimed
EP-1028940-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 2000-08-23 — — EP claimed
WO-1999024393-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 1999-05-20 — — WO claimed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 — — CN claimed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065219-A1 PROCESS TO PRODUCE OXAZOLIDINONES ADH1A, ADH5, ADH1C ALDH1A1 109/4885KDM4E 2057/4885MAPT 3538/4885
US-20030130509-A1 PROCESS TO PRODUCE 3-CARBON AMINO ALCOHOL SALTS ADH1A, ADH5, ADH1C ALDH1A1 73/4885KDM4E 2039/4885MAPT 3318/4885
US-20040006238-A1 Process to produce oxazolidinones ADH1A, ADH5, ADH1C ALDH1A1 142/4885KDM4E 2156/4885MAPT 3496/4885
US-20020095054-A1 Process to produce oxazolidinones ADH1A, ADH5, ADH1C ALDH1A1 109/4885KDM4E 2057/4885MAPT 3538/4885
US-20030216572-A1 PROCESS TO PRODUCE OXAZOLIDINONES ADH1A, ADH5, ADH1C ALDH1A1 109/4885KDM4E 2057/4885MAPT 3538/4885
US-20020032348-A1 Process to produce oxazolidinones ADH1A, ADH5, ADH1C ALDH1A1 109/4885KDM4E 2057/4885MAPT 3538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.