Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616820 | 0.97 | TMEM97 (0.62) | TMEM97SIGMAR1 | |
| SCHEMBL21616830 | 0.92 | SIGMAR1 (0.63) | TMEM97SIGMAR1 | |
| SCHEMBL12124517 | 0.86 | — | — | |
| SCHEMBL15958316 | 0.82 | HTR1A (0.59) | — | |
| SCHEMBL12124503 | 0.82 | SLC6A2 (0.72) | — | |
| SCHEMBL21616847 | 0.81 | NPC1 (0.60) | SIGMAR1 | |
| SCHEMBL12124421 | 0.81 | ALDH1A1 (0.72) | — | |
| SCHEMBL21616836 | 0.78 | TMEM97 (0.58) | TMEM97SIGMAR1 | |
| SCHEMBL12124573 | 0.77 | TMEM97 (0.56) | TMEM97 | |
| SCHEMBL12359956 | 0.76 | SIGMAR1 (0.87) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230131-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) (FR) | 2021-07-29 | — | — | US | disclosed |
| EP-3820862-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-05-19 | — | — | EP | disclosed |
| WO-2020011848-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2020-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230131-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | ABCG2, SLC10A1, CYP3A43 | TMEM97 1765/4885SIGMAR1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.