SCHEMBL21617165

SCHEMBL21617165

CC(C)(C)c1cc(OCc2ccccc2)ccc1Nc1ccccc1C(=O)NCCC1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 3/20 0.46
▸ MAOA P21397 1/20 0.46
▸ CHRM4 P08173 7/20 0.45
▸ BRD4 O60885 1/20 0.44
▸ SGMS2 Q8NHU3 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ CTSV O60911 1/20 0.42
▸ CTSL P07711 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31504355 1.00 MAOB (0.46) MAOBMAOACHRM4BRD4SGMS2
SCHEMBL31504389 0.90 MAOB (0.47) MAOBMAOACHRM4BRD4SGMS2
SCHEMBL21617188 0.90 MAOB (0.47) MAOBMAOACHRM4BRD4SGMS2
SCHEMBL21617306 0.87 MAOB (0.46) MAOBMAOACHRM4BRD4SGMS2
SCHEMBL31504451 0.87 MAOB (0.46) MAOBMAOACHRM4BRD4SGMS2
SCHEMBL21617278 0.84 SIRT2 (0.58) MAOBMAOACHRM4SGMS2KMT2A
SCHEMBL31504450 0.84 SIRT2 (0.58) MAOBMAOACHRM4SGMS2KMT2A
SCHEMBL21617297 0.82 SGMS2 (0.43) MAOBMAOACHRM4SGMS2MEN1
SCHEMBL31504359 0.82 SGMS2 (0.43) MAOBMAOACHRM4SGMS2MEN1
SCHEMBL21617230 0.81 CTSV (0.62) MAOBCHRM4MEN1KMT2ACTSV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-09-23 — — US disclosed
EP-3820850-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 — — EP disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection NSUN3, CBR3, C1R MAOB 2297/4885MAOA 1648/4885CHRM4 1202/4885
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION NSUN3, CBR3, C1R MAOB 2297/4885MAOA 1648/4885CHRM4 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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