SCHEMBL21617293

SCHEMBL21617293

O=C(NCCC1CCCC1)c1cccc(Nc2ccc(OCc3ccccn3)cn2)c1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CHRM4 P08173 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ GPR132 Q9UNW8 1/20 0.40
▸ KIT P10721 2/20 0.39
▸ MAPK14 Q16539 2/20 0.39
▸ CYP4F2 P78329 2/20 0.39
▸ CYP4A11 Q02928 2/20 0.39
▸ LCK P06239 1/20 0.39
▸ SRC P12931 1/20 0.39
▸ CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31504424 1.00 CHRM4 (0.41) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL31504383 0.90 GPR132 (0.44) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL21617201 0.90 GPR132 (0.44) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL21617285 0.89 HPGD (0.45) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL31504443 0.89 HPGD (0.45) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL21617237 0.88 GPR132 (0.44) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL31504406 0.88 GPR132 (0.44) CHRM4MEN1HPGDKMT2AGPR132
SCHEMBL21617274 0.86 GPR132 (0.45) CHRM4GPR132MAPK14
SCHEMBL31504336 0.86 GPR132 (0.45) CHRM4GPR132MAPK14
SCHEMBL21617187 0.86 MAPK14 (0.44) GPR132KITMAPK14LCKSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820850-B1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2026-04-01 — — EP disclosed
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-09-23 — — US disclosed
EP-3820850-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 — — EP disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection NSUN3, CBR3, C1R CHRM4 1202/4885MEN1 3986/4885HPGD 3998/4885
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION NSUN3, CBR3, C1R CHRM4 1202/4885MEN1 3986/4885HPGD 3998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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