SCHEMBL216180

SCHEMBL216180

C=Cc1ccc(/C=N/CCNCC/N=C/c2ccc(/C=N/CCNCCN)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.36
CA2 P00918 8/20 0.35
CA9 Q16790 6/20 0.34
CA7 P43166 5/20 0.34
CA12 O43570 5/20 0.34
CA6 P23280 4/20 0.34
CA14 Q9ULX7 4/20 0.34
CA5B Q9Y2D0 4/20 0.34
MEN1 O00255 2/20 0.34
RECQL P46063 2/20 0.34
CA1 P00915 3/20 0.34
CA4 P22748 3/20 0.33
CA5A P35218 3/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CA3 P07451 2/20 0.33
ALOX15 P16050 2/20 0.33
TP53 P04637 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13310259 0.89 CA2 (0.44) ALDH1A1KMT2ACA2CA9CA7
SCHEMBL8760736 0.76 ALDH1A1 (0.34) ALDH1A1KMT2ACA2CA9CA12
Styrene SCHEMBL28247389 0.76 ALDH1A1 (0.58) ALDH1A1KMT2ACA2CA9CA7
SCHEMBL9748097 0.75 SIGMAR1 (0.50) ALDH1A1KMT2ACA2CA9CA7
SCHEMBL7935225 0.74 MC4R (0.45) ALDH1A1KMT2ACA2CA9CA7
SCHEMBL20417365 0.73 ALDH1A1 (0.45) ALDH1A1KMT2ACA2CA9CA7
SCHEMBL4017967 0.73 MC4R (0.47) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL13521702 0.72 ALDH1A1 (0.48) ALDH1A1KMT2ACA2CA9CA7
Hydrochloric Acid SCHEMBL7123283 0.72 MC4R (0.44) ALDH1A1KMT2ACA2CA9CA7
Hydrochloric Acid SCHEMBL7127056 0.71 MC4R (0.46) ALDH1A1KMT2AMEN1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120322054-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-12-20 US disclosed
US-8317999-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-27 US disclosed
US-8313625-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-20 US disclosed
US-8313639-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-20 US disclosed
US-8306757-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-06 US disclosed
US-8293082-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-10-23 US disclosed
US-8269261-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-09-18 US disclosed
US-8264014-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-09-11 US disclosed
US-20120135870-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-31 US disclosed
US-20120129728-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-24 US disclosed
US-20120040844-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20120037961-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20120034607-A1 Methods and apparatus for measuring analytes using large scale fet arrays Life Technologies Corporation (US) 2012-02-09 US disclosed
US-20110247933-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-13 US disclosed
US-20110248319-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-13 US disclosed
US-20110241081-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-06 US disclosed
US-20110230375-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-09-22 US disclosed
US-7948015-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2011-05-24 US disclosed
US-20090127589-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-05-21 US disclosed
US-20090026082-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-01-29 US disclosed