Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560059 | 0.85 | USP2 (0.57) | TDP1ALOX15MAPTTLR8ALDH1A1 | |
| SCHEMBL22560057 | 0.83 | TDP1 (0.65) | TDP1ALOX15MAPTTLR8PDE4B | |
| SCHEMBL2163633 | 0.79 | LMNA (0.49) | TDP1ALOX15MAPTALDH1A1LMNA | |
| SCHEMBL2162368 | 0.79 | TDP1 (0.51) | TDP1ALOX15MAPTTLR8ALDH1A1 | |
| SCHEMBL6287258 | 0.76 | PDE4B (0.50) | TDP1ALOX15MAPTTLR8PDE4B | |
| SCHEMBL6287320 | 0.76 | PDE4B (0.50) | TDP1ALOX15MAPTTLR8PDE4B | |
| SCHEMBL6286533 | 0.76 | PDE4B (0.50) | TDP1ALOX15MAPTTLR8PDE4B | |
| SCHEMBL6287191 | 0.76 | PDE4B (0.50) | TDP1ALOX15MAPTTLR8PDE4B | |
| SCHEMBL6287779 | 0.76 | PDE4B (0.50) | TDP1ALOX15MAPTTLR8PDE4B | |
| SCHEMBL6287907 | 0.76 | PDE4B (0.50) | TDP1ALOX15MAPTTLR8PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513064-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-10-24 | — | — | EP | claimed |
| WO-2011080132-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2011-07-07 | — | — | WO | claimed |