Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560057 | 0.81 | TDP1 (0.65) | LMNATDP1ALOX15MAPTALDH1A1 | |
| SCHEMBL22560059 | 0.80 | USP2 (0.57) | LMNATDP1ALOX15MAPTALDH1A1 | |
| SCHEMBL28138218 | 0.77 | MAPT (0.44) | LMNAAPOBEC3GTDP1ALOX15MAPT | |
| SCHEMBL2162368 | 0.77 | TDP1 (0.51) | LMNAGLATDP1ALOX15MAPT | |
| 4-Nitroaniline SCHEMBL8748697 | 0.69 | ALDH1A1 (0.69) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL26215154 | 0.68 | LMNA (0.45) | LMNAAPOBEC3GGLANPSR1TDP1 | |
| SCHEMBL28824386 | 0.67 | MAPT (0.54) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10824195 | 0.67 | RARB (0.63) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9839611 | 0.67 | RARB (0.63) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9839289 | 0.67 | RARB (0.63) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513064-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-10-24 | — | — | EP | claimed |
| WO-2011080132-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2011-07-07 | — | — | WO | claimed |