Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560057 | 0.81 | TDP1 (0.65) | TDP1ALOX15ALDH1A1LMNATLR8 | |
| SCHEMBL22560059 | 0.80 | USP2 (0.57) | TDP1ALOX15ALDH1A1LMNATLR8 | |
| SCHEMBL2162012 | 0.79 | TDP1 (0.69) | TDP1ALOX15ALDH1A1LMNATLR8 | |
| SCHEMBL2163633 | 0.77 | LMNA (0.49) | TDP1ALOX15ALDH1A1LMNAGLA | |
| SCHEMBL2162636 | 0.76 | USP2 (0.69) | TDP1ALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL18794891 | 0.70 | TDP1 (0.47) | TDP1ALOX15ALDH1A1LMNAMAPT | |
| SCHEMBL10616089 | 0.68 | TSHR (0.58) | TDP1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL594161 | 0.68 | TSHR (0.63) | TDP1ALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL4560849 | 0.67 | TSHR (0.62) | TDP1ALOX15ALDH1A1TLR8MAPT | |
| SCHEMBL15804418 | 0.67 | USP2 (0.44) | TDP1ALOX15ALDH1A1LMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513064-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-10-24 | — | — | EP | claimed |
| WO-2011080132-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2011-07-07 | — | — | WO | claimed |