Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18728445 | 0.93 | HTR7 (0.43) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL29772127 | 0.93 | HTR7 (0.43) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL26636905 | 0.83 | HTR7 (0.44) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL15286819 | 0.81 | MAPT (0.44) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL29648252 | 0.81 | HTR7 (0.43) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL28751083 | 0.81 | CYP1A2 (0.50) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL13555092 | 0.81 | HTR7 (0.43) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL18728167 | 0.81 | HTR7 (0.43) | HTR7HTR1BMAPTL3MBTL1HPGD | |
| SCHEMBL1929353 | 0.80 | HTR7 (0.58) | HTR7MAPTL3MBTL1HPGDRAB9A | |
| SCHEMBL30504433 | 0.80 | HTR1B (0.50) | HTR7HTR1BMAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384500-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112424194-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20220119411-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2022-04-21 | — | — | US | disclosed |
| US-20220119411-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2022-04-21 | — | — | US | disclosed |
| US-20210300909-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2021-09-30 | — | — | US | disclosed |
| CN-112424194-A | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112384500-A | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2021-02-19 | — | — | CN | disclosed |
| WO-2020011243-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119411-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | IL2, IL5, TSLP | HTR7 4158/4885HTR1B 3704/4885MAPT 4396/4885 |
| US-20210300909-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | IL2, IL5, TSLP | HTR7 4158/4885HTR1B 3704/4885MAPT 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.