Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162139 | 0.89 | MEN1 (0.69) | TP53MAPTMEN1KMT2AUSP2 | |
| SCHEMBL2161405 | 0.89 | MAPT (0.73) | TP53MAPTMEN1KMT2AUSP2 | |
| SCHEMBL2162252 | 0.84 | MEN1 (0.62) | TP53MAPTMEN1KMT2ALMNA | |
| SCHEMBL2161438 | 0.77 | MAPT (0.79) | TP53MAPTMEN1KMT2ALMNA | |
| SCHEMBL2162132 | 0.77 | TP53 (0.67) | TP53MAPTMEN1KMT2AUSP2 | |
| SCHEMBL4496691 | 0.77 | PPARG (0.61) | MEN1KMT2A | |
| SCHEMBL2161493 | 0.75 | KMT2A (0.80) | TP53MAPTMEN1KMT2A | |
| SCHEMBL2161690 | 0.75 | MEN1 (0.71) | TP53MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2161515 | 0.75 | MEN1 (0.65) | TP53MAPTMEN1KMT2ALMNA | |
| SCHEMBL2162134 | 0.75 | MEN1 (0.84) | TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985764-B2 | Amide derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1988076-A1 | AMIDE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062363-A1 | AMIDE DERIVATIVE OR SALT THEREOF | HTR7, HTR2B, NPSR1 | TP53 4814/4885MAPT 4469/4885MEN1 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.