Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24479763 | 0.88 | THRB (0.63) | PPARGTHRBMEN1KMT2ATDP1 | |
| SCHEMBL27734727 | 0.86 | PPARG (0.74) | PPARGL3MBTL1THRBMEN1KMT2A | |
| SCHEMBL14121028 | 0.85 | PPARG (0.60) | PPARGTHRBMEN1KMT2ATDP1 | |
| SCHEMBL14233463 | 0.83 | PPARG (0.72) | PPARG | |
| SCHEMBL14234066 | 0.81 | PPARG (0.69) | PPARG | |
| SCHEMBL7414196 | 0.80 | L3MBTL1 (0.65) | PPARGL3MBTL1MEN1KMT2A | |
| SCHEMBL14233803 | 0.80 | PPARG (0.67) | PPARG | |
| SCHEMBL14211663 | 0.80 | PPARG (0.71) | PPARG | |
| SCHEMBL14211634 | 0.80 | PPARG (0.71) | PPARG | |
| SCHEMBL14241614 | 0.79 | PPARG (0.61) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | PPARG 1583/4885L3MBTL1 2144/4885THRB 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.