Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621454 | 0.92 | ADORA3 (0.60) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL21621458 | 0.91 | ADORA3 (0.57) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL1664667 | 0.84 | ADORA3 (1.00) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| Pentaacetylquercetin SCHEMBL4064499 | 0.81 | ADORA3 (0.77) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| Kaempferol Tetraacetate SCHEMBL10379364 | 0.81 | ADORA3 (0.84) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL23278846 | 0.78 | ADORA3 (0.72) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL21819719 | 0.78 | ADORA3 (0.72) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL20581611 | 0.78 | ADORA3 (0.78) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL22710236 | 0.77 | ADORA3 (0.42) | ADORA3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL28377445 | 0.77 | ADORA3 (0.77) | ADORA3KDM4EMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139447-A1 | Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS) | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-05-13 | — | — | US | disclosed |
| WO-2020012003-A1 | LIPOPHENOLIC FLAVONOID DERIVATIVES USEFUL TO REDUCE CARBONYL AND OXIDATIVE STRESSES (COS) | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2020-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139447-A1 | Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS) | LPO, NQO1, CAT | ADORA3 4848/4885KDM4E 3213/4885MAPT 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.