Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551661 | 1.00 | ITGB1 (0.44) | ITGB1ITGA4PBRM1TAS1R3TAS1R1 | |
| SCHEMBL4975149 | 0.99 | ITGB1 (0.43) | ITGB1ITGA4PBRM1TAS1R3TAS1R1 | |
| SCHEMBL551662 | 0.89 | TAS1R3 (0.45) | ITGB1ITGA4PBRM1TAS1R3TAS1R1 | |
| SCHEMBL550830 | 0.88 | TAS1R3 (0.42) | ITGB1ITGA4PBRM1TAS1R3TAS1R1 | |
| Lithium Ion SCHEMBL4975146 | 0.87 | ITGB1 (0.40) | ITGB1ITGA4TAS1R3TAS1R1TAS1R2 | |
| Lithium Ion SCHEMBL5498755 | 0.87 | ITGB1 (0.40) | ITGB1ITGA4TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14534476 | 0.85 | L3MBTL1 (0.44) | TSHRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2161524 | 0.85 | ALDH1A1 (0.38) | TAS1R3TAS1R1TAS1R2TSHRMEN1 | |
| SCHEMBL551263 | 0.84 | KMT2A (0.41) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL552115 | 0.84 | MEN1 (0.41) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | ITGB1 4654/4885ITGA4 4753/4885PBRM1 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.