SCHEMBL2162181

SCHEMBL2162181

O=C(O)c1cccc(C(=O)O)c1S

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
ALDH1A1 P00352 4/20 0.60
ALOX15 P16050 1/20 0.60
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
TSHR P16473 1/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
HMGB1 P09429 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA7 P43166 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CA9 Q16790 1/20 0.50
NAPRT Q6XQN6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9895331 0.89 MAPT (0.50) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL8511204 0.87 MAPT (0.67) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL7249581 0.87 MAPT (0.48) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL16534312 0.85 ALDH1A1 (0.60) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL2960119 0.84 ALDH1A1 (0.61) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL14690636 0.84 ALB (0.61) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL4007741 0.84 TSHR (0.63) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL16534281 0.84 PRNP (0.50) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL1157782 0.84 MMP2 (0.61) MAPTHDAC8ALDH1A1ALOX15KDM4E
SCHEMBL22261814 0.82 CYP1A2 (0.58) MAPTHDAC8ALDH1A1ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470451-B2 Binding agent component for surface coating agents with improved adhesive properties HENKEL AG & CO. KGAA (DE) 2008-12-30 US claimed
JP-60190389-A None JP disclosed
US-10280346-B2 One-part curable adhesive composition and the use thereof HENKEL AG & CO. KGAA (DE) 2019-05-07 US disclosed
EP-2892934-B1 POLYURETHANE/POLYACRYLIC HYBRID DISPERSIONS FOR SHINE APPLICATIONS IN HOME CARE LUBRIZOL ADVANCED MAT INC (US) 2019-04-10 EP disclosed
EP-3289038-A1 A ONE-PART CURABLE ADHESIVE COMPOSITIONAND THE USE THEREOF Henkel AG & Co. KGaA (DE) 2018-03-07 EP disclosed
US-20180044565-A1 ONE-PART CURABLE ADHESIVE COMPOSITION AND THE USE THEREOF HENKEL AG & CO. KGAA (DE) 2018-02-15 US disclosed
US-9856435-B2 Polyurethane/polyacrylic hybrid dispersions for shine applications in home care LUBRIZOL ADVANCED MATERIALS, INC. (US) 2018-01-02 US disclosed
WO-2016172911-A1 A ONE-PART CURABLE ADHESIVE COMPOSITIONAND THE USE THEREOF HENKEL AG & CO. KGAA (DE) 2016-11-03 WO disclosed
US-20150315527-A1 Polyurethane/Polyacrylic Hybrid Dispersions For Shine Applications In Home Care LUBRIZOL ADVANCED MATERIALS, INC. 2015-11-05 US disclosed
EP-2892934-A1 POLYURETHANE/POLYACRYLIC HYBRID DISPERSIONS FOR SHINE APPLICATIONS IN HOME CARE Lubrizol Advanced Materials, Inc. (US) 2015-07-15 EP disclosed
WO-1991004990-A1 STABLE EMULSION POLYMERS AND METHODS OF PREPARING SAME S.C. JOHNSON & SON, INC. (US) 1991-04-18 WO disclosed
EP-0420097-A2 Coreactable powdered compositions UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1991-04-03 EP disclosed
US-4894397-A CORE-SHELL LATEX, FILMS, ADDITION POLYMERIZATION S. C. JOHNSON & SON, INC. (US) 1990-01-16 US disclosed
EP-0338486-A2 Stable emulsion polymers and methods of preparing same S.C. JOHNSON & SON, INC. (US) 1989-10-25 EP disclosed
US-4628071-A Emulsion copolymerization process S. C. JOHNSON & SON, INC. (US) 1986-12-09 US disclosed
JP-S60190389-A SHEET FOR HEAT TRANSFER COLOR RECORDING MITSUBISHI CHEM IND LTD 1985-09-27 JP disclosed
US-4368320-A CROSSLINKABLE WITH POLYISOCYANATES; VARNISHES DEGUSSA AKTIENGESELLSCHAFT (DE) 1983-01-11 US disclosed
EP-0000601-B1 PROCESS FOR THE PREPARATION OF A LOW MOLECULAR WEIGHT ACRYLATE COPOLYMER, AND A LIQUID COATING COMPOSITION HAVING A HIGH SOLIDS CONTENT BASED ON THE ACRYLATE COPOLYMER THUS OBTAINED AKZO N.V. (NL) 1981-08-26 EP disclosed
US-4245074-A POLYMERIZATION IN PRESENCE OF A MERCAPTOCARBOXYLIC ACID, REACTION WITH A GLYCIDYL ESTER OF A MONOCARBOXYLIC ACID AKZO N.V. (NL) 1981-01-13 US disclosed
EP-0000601-A1 Process for the preparation of a low molecular weight acrylate copolymer, and a liquid coating composition having a high solids content based on the acrylate copolymer thus obtained AKZO N.V. (NL) 1979-02-07 EP disclosed