Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.41 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.41 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.40 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162181 | 0.87 | MAPT (0.61) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL29098719 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL589207 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL29098715 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL192153 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL7030044 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL29098718 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL7030041 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL29726051 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD | |
| Phthalic Acid SCHEMBL29098716 | 0.78 | ALDH1A1 (0.70) | MAPTHDAC8ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635347-B1 | Blended dyed product of fiber dyeable with disperse dye and polyurethane fiber and dyeing method therefor | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-10-21 | — | — | US | disclosed |
| EP-1152083-A1 | BLENDED DYED PRODUCT OF FIBER DYEABLE WITH DISPERSE DYE AND POLYURETHANE FIBER AND DYEING METHOD THEREFOR | Asahi Kasei Kabushiki Kaisha (JP) | 2001-11-07 | — | — | EP | disclosed |