Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 10/20 | 0.63 |
| ▸ | ERCC4 | Q92889 | 10/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30519963 | 1.00 | ERCC1 (0.63) | ERCC1ERCC4ALPLMT-CO2ALOX5 | |
| SCHEMBL30686688 | 0.89 | ALOX5 (0.60) | ALOX5TERTAPEX1 | |
| SCHEMBL24402990 | 0.89 | ALOX5 (0.60) | ALOX5TERTAPEX1 | |
| SCHEMBL1470838 | 0.87 | ALOX5 (0.62) | ALOX5TERTAPEX1 | |
| SCHEMBL14698338 | 0.83 | APEX1 (0.59) | ALOX5ALOX15APEX1 | |
| SCHEMBL14081423 | 0.82 | MT-CO2 (0.65) | ERCC1ERCC4ALPLMT-CO2ALPG | |
| SCHEMBL30520585 | 0.82 | APEX1 (0.58) | ALOX5ALOX15APEX1 | |
| SCHEMBL21623922 | 0.82 | APEX1 (0.58) | ALOX5ALOX15APEX1 | |
| SCHEMBL3192733 | 0.82 | KMT2A (0.67) | ALOX5APEX1 | |
| SCHEMBL18285049 | 0.82 | ALOX5 (0.53) | ALOX5TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911172-A1 | COMBINATION REMEDY | Symrise AG (DE) | 2021-11-24 | — | — | EP | disclosed |
| EP-3823455-A1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | Symrise AG (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020147977-A1 | COMBINATION REMEDY | SYMRISE AG (DE) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020015816-A1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | SYMRISE AG (DE) | 2020-01-23 | — | — | WO | disclosed |