Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14698338 | 0.99 | APEX1 (0.59) | APEX1TRPV1HPGDALDH1A1CYP1A2 | |
| SCHEMBL30520585 | 0.97 | APEX1 (0.58) | APEX1TRPV1HPGDALDH1A1CYP1A2 | |
| SCHEMBL1031773 | 0.90 | TRPV1 (0.59) | APEX1TRPV1HPGDALDH1A1CYP1A2 | |
| SCHEMBL21623925 | 0.86 | HPGD (0.53) | APEX1HPGDALDH1A1ALOX15ALOX5 | |
| SCHEMBL899104 | 0.85 | PTPN7 (0.53) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30386504 | 0.84 | APEX1 (0.56) | APEX1TRPV1HPGDTP53GLA | |
| SCHEMBL898313 | 0.83 | PTPN7 (0.54) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21623928 | 0.82 | ERCC1 (0.63) | APEX1ALOX15ALOX5 | |
| SCHEMBL30519963 | 0.82 | ERCC1 (0.63) | APEX1ALOX15ALOX5 | |
| SCHEMBL20448914 | 0.82 | ALDH1A1 (0.62) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911172-A1 | COMBINATION REMEDY | Symrise AG (DE) | 2021-11-24 | — | — | EP | disclosed |
| EP-3823455-A1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | Symrise AG (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020147977-A1 | COMBINATION REMEDY | SYMRISE AG (DE) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020015816-A1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | SYMRISE AG (DE) | 2020-01-23 | — | — | WO | disclosed |