Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TYMS | P04818 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174540 | 1.00 | NPC1 (0.63) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25169249 | 0.98 | NPC1 (0.61) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2163036 | 0.86 | TYMS (0.52) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL17747821 | 0.84 | TYMS (0.51) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10966414 | 0.81 | TYMS (0.63) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10833674 | 0.81 | PLAU (0.51) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29439014 | 0.80 | KDM4E (0.61) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4371528 | 0.80 | KDM4E (0.61) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7240766 | 0.79 | CBFB (0.51) | NPC1TP53HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9304583 | 0.79 | NPC1 (0.58) | NPC1TP53HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | claimed |
| CN-105384693-B | Compound, its synthetic method and the purposes of the structure of bisazo containing benzoxazole ring | 盐城工学院 | 2018-11-09 | — | — | CN | claimed |
| CN-105384693-A | Compound containing benzoxazole ring bis(azo) structure, synthetic method for compound and use of compound | YANCHENG INST TECHNOLOGY | 2016-03-09 | — | — | CN | claimed |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-05-30 | — | — | US | claimed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | claimed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| US-20250066411-A1 | GLYCOMIMETIC BINDERS FOR L-SIGN | UNIVERSITA’ DEGLI STUDI DI MILANO (IT) | 2025-02-27 | — | — | US | disclosed |
| CN-114423763-B | Regioselective synthesis of imidazo [1,2-a ] pyrimidines | 豪夫迈·罗氏有限公司 | 2025-01-21 | — | — | CN | disclosed |
| US-20240182454-A1 | Polycyclic Compound for Inhibiting RNA Helicase DHX33, and Application of Compound | SHENZHEN KEYE LIFE TECHNOLOGIES, CO., LTD (CN) | 2024-06-06 | — | — | US | disclosed |
| EP-4378940-A1 | POLYCYCLIC COMPOUND FOR INHIBITING RNA HELICASE DHX33, AND APPLICATION OF COMPOUND | Shenzhen Keye Life Technologies, Co., Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |
| CN-114989096-B | Thioazole compound and preparation method and application thereof | 赣南师范大学 | 2023-10-24 | — | — | CN | disclosed |
| US-20230210966-A1 | EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES WITH POTASSIUM CHANNEL AGONISTS AND THERAPEUTIC USES THEREOF | LION BIOTECHNOLOGIES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-4237292-A | SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237286-A | COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237293-A | COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4132708-A | Metal complexes of azomethines and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4111947-A | DYES, PLASTICS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4065462-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4022770-A | COLORING | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210966-A1 | EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES WITH POTASSIUM CHANNEL AGONISTS AND THERAPEUTIC USES THEREOF | KCNN3, KCNK3, KCNA3 | NPC1 1119/4885TP53 389/4885HPGD 3091/4885 |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | FLNB, BRI3BP, CCNI | NPC1 4849/4885TP53 3199/4885HPGD 1588/4885 |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | FLNB, BRI3BP, CCNI | NPC1 4849/4885TP53 3199/4885HPGD 1588/4885 |
| US-20250066411-A1 | GLYCOMIMETIC BINDERS FOR L-SIGN | HAVCR2, SIGLEC9, SIGLEC7 | NPC1 2196/4885TP53 140/4885HPGD 4464/4885 |
| US-20240182454-A1 | Polycyclic Compound for Inhibiting RNA Helicase DHX33, and Application of Compound | DHX36, DDX3X, DDX21 | NPC1 825/4885TP53 959/4885HPGD 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.