SCHEMBL21625243

SCHEMBL21625243

OC[C@H]1O[C@@H](n2cnc3cncnc32)C[C@@H]1O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.60
PNP P00491 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
HTT P42858 1/20 0.53
PDE4D Q08499 1/20 0.53
PDE3A Q14432 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
PIM1 P11309 1/20 0.52
CSNK2A2 P19784 1/20 0.52
CSNK2B P67870 1/20 0.52
CSNK2A1 P68400 1/20 0.52
CSNK2A3 Q8NEV1 1/20 0.52
ADRB1 P08588 1/20 0.52
DNMT1 P26358 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3516851 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL12595406 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL4412045 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL5981719 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL3516854 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL5981711 1.00 HIF1A (0.60) HIF1APNPLMNATP53HTT
SCHEMBL14429235 0.92 HIF1A (0.51) HIF1APNPLMNATP53HTT
SCHEMBL26298184 0.89 HIF1A (0.50) HIF1APNPLMNATP53HTT
SCHEMBL14580420 0.86 HIF1A (0.45) HIF1APNPLMNATP53HTT
SCHEMBL19392034 0.83 HIF1A (0.43) HIF1APNPLMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113913497-B Method for detecting target nucleic acid by using single-stranded nucleic acid modified by base 山东舜丰生物科技有限公司 2024-05-28 CN claimed
EP-4323517-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSICOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2024-02-21 EP claimed
WO-2023141604-A2 METHODS OF MOLECULAR TAGGING FOR SINGLE-CELL ANALYSIS MISSION BIO, INC. (US) 2023-07-27 WO claimed
WO-2022219409-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSICOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2022-10-20 WO claimed
CN-109863161-B Labeled polynucleotides useful for nucleic acid sequencing 豪夫迈·罗氏有限公司 2022-06-03 CN claimed
EP-4743590-A1 MICROBIOME ANALYSIS Readygo Diagnostics Limited (GB) 2026-05-20 EP disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
EP-4698678-A1 A METHOD FOR PROFILING OF MUTATIONS VIA GAP FILLING ON RNA AND A KIT FOR USE IN A METHOD FOR PROFILING OF MUTATIONS Voxlbio AB (SE) 2026-02-25 EP disclosed
EP-4689159-A1 METHOD AND KITS Oxford Nanopore Technologies PLC (GB) 2026-02-11 EP disclosed
WO-2025235935-A1 METHODS OF SYNTHESIZING NUCLEIC ACID MOLECULES TELESIS BIO INC (US) 2025-11-13 WO disclosed
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF SHIVALILA CHIKDU SHAKTI (US) 2025-10-02 US disclosed
US-20250262235-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD (SG) 2025-08-21 US disclosed
CN-109863161-B Labeled polynucleotides useful for nucleic acid sequencing 豪夫迈·罗氏有限公司 2022-06-03 CN disclosed
CN-107002151-B Method of delivering an analyte to a transmembrane pore 牛津纳米孔技术公司 2022-04-01 CN disclosed
CN-114107457-A Method of delivering an analyte to a transmembrane pore 牛津纳米孔技术公司 2022-03-01 CN disclosed
US-20210277046-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS JANSSEN PHARMACEUTICA NV (BE) 2021-09-09 US disclosed
US-20210277046-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS JANSSEN PHARMACEUTICA NV (BE) 2021-09-09 US disclosed
EP-3823976-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS Janssen Biotech, Inc. (US) 2021-05-26 EP disclosed
CN-112424212-A Cyclic dinucleotides as STING agonists 詹森生物科技公司 2021-02-26 CN disclosed
WO-2020016782-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS JANSSEN BIOTECH, INC. (US) 2020-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF ADAR, NSUN2, RNGTT HIF1A 1187/4885PNP 55/4885LMNA 793/4885
US-20250262235-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO ADAR, RNGTT, NSUN2 HIF1A 2305/4885PNP 56/4885LMNA 1350/4885
US-20210277046-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS STING1, CGAS, IFNAR1 HIF1A 1415/4885PNP 319/4885LMNA 653/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 HIF1A 1162/4885PNP 487/4885LMNA 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.