Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21625708 | 0.99 | MCHR1 (0.50) | MCHR1TMEM97SIGMAR1ACKR3LMNA | |
| SCHEMBL23983050 | 0.95 | POLB (0.49) | MCHR1TMEM97SIGMAR1ACKR3LMNA | |
| Hydrochloric Acid SCHEMBL21625700 | 0.94 | POLB (0.49) | MCHR1TMEM97SIGMAR1ACKR3LMNA | |
| SCHEMBL21625706 | 0.93 | MCHR1 (0.47) | MCHR1TMEM97SIGMAR1ACKR3LMNA | |
| Hydrochloric Acid SCHEMBL21625704 | 0.92 | MCHR1 (0.46) | MCHR1TMEM97SIGMAR1ACKR3LMNA | |
| SCHEMBL21625702 | 0.88 | MCHR1 (0.51) | MCHR1POLBBCHEACHEHTR2C | |
| SCHEMBL23983072 | 0.88 | DRD2 (0.46) | MCHR1DRD2DRD3POLBRAD52 | |
| Hydrochloric Acid SCHEMBL21625731 | 0.87 | MCHR1 (0.50) | MCHR1POLBBCHEACHEHTR2C | |
| Hydrochloric Acid SCHEMBL21625726 | 0.87 | DRD2 (0.45) | MCHR1DRD2DRD3POLBRAD52 | |
| SCHEMBL21625723 | 0.87 | HSD17B1 (0.51) | MCHR1TMEM97SIGMAR1ACKR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340119-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | HEXAPHARMATEC CO., LTD. (KR) | 2021-11-04 | — | — | US | disclosed |
| US-20210340119-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | HEXAPHARMATEC CO., LTD. (KR) | 2021-11-04 | — | — | US | disclosed |
| EP-3814340-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Hexapharmatec Co., Ltd. (KR) | 2021-05-05 | — | — | EP | disclosed |
| WO-2020017878-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | HEXAPHARMATEC CO., LTD. (KR) | 2020-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340119-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | COMT, TYR, REN | MCHR1 745/4885TMEM97 2337/4885SIGMAR1 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.