SCHEMBL2162585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16183310	0.89	KMT2A (0.52)	CYP11B1CYP11B2GBA1PDE5ACYP19A1
	Hydrochloric Acid SCHEMBL7280022	0.88	PDE5A (0.52)	CYP11B1CYP11B2GBA1PDE5ACYP19A1
	SCHEMBL14727426	0.86	PDE5A (0.53)	CYP11B1CYP11B2PDE5AKMT2AALDH1A1
	SCHEMBL13312483	0.84	HTT (0.47)	PDE5AKMT2ACYP1A2MEN1LMNA
	SCHEMBL14358473	0.83	CYP11B1 (0.49)	CYP11B1CYP11B2GBA1PDE5ACYP19A1
	SCHEMBL14727632	0.83	CYP1A2 (0.50)	CYP11B1CYP11B2GBA1PDE5ACYP19A1
	Hydrochloric Acid SCHEMBL7288904	0.82	PDE5A (0.60)	CYP11B1CYP11B2GBA1PDE5AKMT2A
	SCHEMBL16183994	0.81	ALDH1A1 (0.44)	PDE5AKMT2AALDH1A1CYP1A2CYP3A4
	SCHEMBL7286466	0.81	ALDH1A1 (0.62)	GBA1PDE5AKMT2AALDH1A1CYP1A2
	SCHEMBL29416346	0.81	ALDH1A1 (0.62)	GBA1PDE5AKMT2AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.