Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23396951 | 0.84 | HDAC3 (0.60) | L3MBTL1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL1950782 | 0.81 | HDAC8 (0.46) | L3MBTL1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL2739420 | 0.79 | ALDH1A1 (0.59) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL28746329 | 0.78 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL1916615 | 0.78 | POLB (0.56) | L3MBTL1MEN1KMT2ACA1CA2 | |
| SCHEMBL10879959 | 0.78 | PSMB11 (0.61) | L3MBTL1MEN1KMT2ACA1CA2 | |
| SCHEMBL21597970 | 0.77 | PSMB11 (0.63) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL10891781 | 0.77 | PSMB11 (0.63) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL9122651 | 0.77 | PSMB11 (0.63) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL3865176 | 0.77 | PSMB11 (0.63) | MEN1KMT2AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020015698-A1 | METHOD FOR PREPARING COAGULATION FACTOR XIA INHIBITOR AND INTERMEDIATE THEREOF | 江苏恒瑞医药股份有限公司 | 2020-01-23 | — | — | WO | disclosed |