Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | TPO | P07202 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626576 | 0.86 | ALDH1A1 (0.39) | NR3C1PGRNR3C2ARHTT | |
| SCHEMBL17629754 | 0.86 | NR3C1 (0.38) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL17629385 | 0.80 | SCN8A (0.42) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL18327656 | 0.80 | NR3C1 (0.44) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL19945739 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SCN8ASCN10A | |
| SCHEMBL23386428 | 0.79 | NR3C1 (0.43) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL16138211 | 0.78 | F11 (0.45) | NR3C1PGRNR3C2ARHTT | |
| SCHEMBL19945621 | 0.78 | F11 (0.46) | HTTALDH1A1LMNA | |
| SCHEMBL18061833 | 0.77 | NR3C1 (0.38) | NR3C1PGRNR3C2ARALDH1A1 | |
| SCHEMBL23843036 | 0.76 | ERN1 (0.46) | NR3C1PGRNR3C2ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020015698-A1 | METHOD FOR PREPARING COAGULATION FACTOR XIA INHIBITOR AND INTERMEDIATE THEREOF | 江苏恒瑞医药股份有限公司 | 2020-01-23 | — | — | WO | disclosed |