Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187849 | 0.86 | KYNU (0.62) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL29678939 | 0.86 | KYNU (0.62) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL269404 | 0.86 | KYNU (0.62) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL18082610 | 0.85 | KYNU (0.60) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL12903901 | 0.85 | KYNU (0.60) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL1068881 | 0.85 | KYNU (0.60) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL19420848 | 0.83 | KYNU (0.58) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL13435790 | 0.82 | KYNU (0.57) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL535707 | 0.82 | KYNU (0.57) | KYNUELANEALDH1A1TRPM8ALOX15 | |
| SCHEMBL19410220 | 0.82 | KYNU (0.57) | KYNUELANEALDH1A1TRPM8ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696716-B2 | Pharmaceutically relevant aromatic-cationic peptides | STEALTH BIOTHERAPEUTICS CORP (MC) | 2020-06-30 | — | — | US | disclosed |
| US-20200024308-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | STEALTH BIOTHERAPEUTICS CORP (MC) | 2020-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200024308-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | ADM2, VIP, ANPEP | KYNU 340/4885ELANE 1423/4885ALDH1A1 4716/4885 |
| US-10696716-B2 | Pharmaceutically relevant aromatic-cationic peptides | ADM2, VIP, ANPEP | KYNU 340/4885ELANE 1423/4885ALDH1A1 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.