SCHEMBL21628231

SCHEMBL21628231

COc1ccc2c(c1)Oc1ccccc1N2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 6/20 0.59
MAPT P10636 6/20 0.53
TDP1 Q9NUW8 3/20 0.53
KMT2A Q03164 3/20 0.53
NOX1 Q9Y5S8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 2/20 0.53
MEN1 O00255 2/20 0.53
GAA P10253 1/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
POLB P06746 2/20 0.50
KDM4E B2RXH2 2/20 0.50
TRPA1 O75762 1/20 0.49
SNCA P37840 1/20 0.47
TP53 P04637 2/20 0.46
HTR2B P41595 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31191629 1.00 ALOX5 (0.59) ALOX5MAPTTDP1KMT2ANOX1
SCHEMBL34467599 0.91 SNCA (0.55) ALOX5MAPTTDP1KMT2ANOX1
SCHEMBL13461776 0.91 SNCA (0.55) ALOX5MAPTTDP1KMT2ANOX1
SCHEMBL11535682 0.90 ALOX5 (0.59) ALOX5MAPTTDP1KMT2ANOX1
SCHEMBL31191638 0.90 ALOX5 (0.59) ALOX5MAPTTDP1KMT2ANOX1
SCHEMBL5739380 0.82 MAPT (0.73) ALOX5MAPTTDP1KMT2AL3MBTL1
SCHEMBL21753467 0.80 KMT2A (0.43) MAPTTDP1KMT2ANOX1L3MBTL1
SCHEMBL9876953 0.80 ALOX5 (0.55) ALOX5MAPTTDP1KMT2AL3MBTL1
SCHEMBL5739379 0.80 MAPT (0.52) ALOX5MAPTTDP1KMT2ANOX1
SCHEMBL20888470 0.79 ALOX5 (0.53) ALOX5MAPTTDP1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025091026-A1 THERAPEUTIC COMPOSITIONS CONTAINING G-CLAMP PNA AND USES THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-05-01 WO claimed
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US claimed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US claimed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP claimed
CN-112513238-A Stable compositions comprising leuco compounds 美利肯公司 2021-03-16 CN claimed
WO-2020023812-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2020-01-30 WO claimed
US-20200032173-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2020-01-30 US claimed
US-20200032167-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY 2020-01-30 US claimed
WO-2025091026-A1 THERAPEUTIC COMPOSITIONS CONTAINING G-CLAMP PNA AND USES THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-05-01 WO disclosed
WO-2023245297-A1 FERROPTOSIS INHIBITORS AND USES THEREOF UNIVERSITY OF OTTAWA (CA) 2023-12-28 WO disclosed
US-20230392018-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY 2023-12-07 US disclosed
EP-4237498-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS Milliken & Company (US) 2023-09-06 EP disclosed
WO-2022093189-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY (US) 2022-05-05 WO disclosed
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US disclosed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US disclosed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP disclosed
CN-112513238-A Stable compositions comprising leuco compounds 美利肯公司 2021-03-16 CN disclosed
US-20200032173-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2020-01-30 US disclosed
WO-2020023812-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2020-01-30 WO disclosed
US-20200032167-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY 2020-01-30 US disclosed