Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997080 | 0.92 | LMNA (0.50) | ALOX5MAPTMEN1USP2ALDH1A1 | |
| SCHEMBL23964033 | 0.92 | LMNA (0.50) | ALOX5MAPTMEN1USP2ALDH1A1 | |
| SCHEMBL1439691 | 0.85 | CYP3A4 (0.49) | ALOX5MAPTMEN1USP2ALDH1A1 | |
| SCHEMBL11194273 | 0.80 | ALOX5 (0.46) | ALOX5MAPTMEN1USP2ALDH1A1 | |
| SCHEMBL21628231 | 0.80 | ALOX5 (0.59) | ALOX5MAPTMEN1ALDH1A1LMNA | |
| SCHEMBL31191629 | 0.80 | ALOX5 (0.59) | ALOX5MAPTMEN1ALDH1A1LMNA | |
| SCHEMBL20888470 | 0.76 | ALOX5 (0.53) | ALOX5MAPTMEN1ALDH1A1LMNA | |
| Bicarbonate SCHEMBL6271299 | 0.75 | MAOB (0.50) | ALOX5MAPTTDP1L3MBTL1 | |
| SCHEMBL9170332 | 0.74 | ALOX5 (0.47) | ALOX5MAPTHTR2BTDP1L3MBTL1 | |
| SCHEMBL4859644 | 0.74 | ALOX5 (0.74) | ALOX5MAPTMEN1KMT2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5035998-A | Hydrolase substrates | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-30 | — | — | US | disclosed |
| US-4900822-A | New hydrolase substrates | BOEHRINGER MANNHEIM GMBH (DE) | 1990-02-13 | — | — | US | disclosed |