SCHEMBL21628405

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628737	0.98	KMT2A (0.43)	FEN1ALOX5APMRGPRX4KMT2AKDM4E
	SCHEMBL20482060	0.96	KMT2A (0.45)	FEN1ALOX5APMRGPRX4KMT2AKDM4E
	SCHEMBL21628889	0.96	KMT2A (0.45)	FEN1ALOX5APMRGPRX4KMT2AKDM4E
	SCHEMBL21628617	0.95	MRGPRX4 (0.46)	FEN1ALOX5APMRGPRX4PTGER4PARP10
	SCHEMBL21628753	0.89	PARP10 (0.46)	FEN1ALOX5APPARP10
	SCHEMBL21628664	0.87	HDAC6 (0.49)	—
	SCHEMBL21628393	0.87	ALOX5AP (0.45)	FEN1ALOX5APSMN1; SMN2HAO1
	SCHEMBL21628434	0.87	PARP10 (0.46)	FEN1ALOX5APHAO1PARP10
	SCHEMBL21628743	0.86	ALDH1A1 (0.40)	FEN1ALOX5APSMN1; SMN2HAO1PARP10
	SCHEMBL21628418	0.86	PARP10 (0.45)	FEN1ALOX5APKMT2AKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.