SCHEMBL21628534

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628547	0.97	HPGD (0.43)	SMN1; SMN2HPGDTSHRHTTRAF1
	SCHEMBL21628391	0.92	HPGD (0.44)	SMN1; SMN2HPGDTSHRHTTRAF1
	SCHEMBL21628668	0.90	HDAC6 (0.42)	PTGER4
	SCHEMBL21628570	0.88	LMNA (0.46)	SMN1; SMN2HPGDPTGER4LIPELMNA
	SCHEMBL21628409	0.88	HPGD (0.44)	SMN1; SMN2HPGDTSHRHTTRAF1
	SCHEMBL21628565	0.88	RAF1 (0.48)	SMN1; SMN2HPGDTSHRHTTRAF1
	SCHEMBL21628419	0.87	HDAC6 (0.42)	PTGER4
	SCHEMBL21628543	0.86	PTGER4 (0.43)	SMN1; SMN2PTGER4SCN9ALMNA
	SCHEMBL21628610	0.85	SMN1; SMN2 (0.39)	SMN1; SMN2PTGER4HPGDSICAM1SELE
	SCHEMBL21628439	0.85	SMN1; SMN2 (0.47)	SMN1; SMN2HPGDTSHRHTTRAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.