SCHEMBL21628583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628450	0.98	PARP10 (0.61)	PARP10PARP15PARP14ALDH1A1KMT2A
	SCHEMBL21628781	0.98	PARP10 (0.61)	PARP10PARP15PARP14ALDH1A1KMT2A
	SCHEMBL21628902	0.97	PARP10 (0.63)	PARP10PARP15PARP14ALDH1A1KMT2A
	SCHEMBL21628546	0.93	PARP10 (0.68)	PARP10PARP15PARP14ALDH1A1KMT2A
	SCHEMBL24124102	0.90	PARP10 (0.52)	PARP10PARP15PARP14ALDH1A1KMT2A
	SCHEMBL17963141	0.89	HDAC8 (0.61)	PARP10PARP15HDAC1HDAC8HDAC6
	SCHEMBL2744667	0.88	HDAC8 (0.59)	PARP10PARP15KMT2AHDAC1HDAC8
	Hydrochloric Acid SCHEMBL4986176	0.86	HDAC8 (0.58)	PARP10PARP15KMT2AHDAC1HDAC8
	SCHEMBL21656947	0.85	PARP10 (0.53)	PARP10PARP15ALDH1A1KMT2AHDAC1
	SCHEMBL21656839	0.83	KMO (0.53)	PARP10PARP15ALDH1A1KMT2AHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.