SCHEMBL21628709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628543	0.96	PTGER4 (0.43)	PTGER4SMN1; SMN2PTGER2PPARGLTA4H
	SCHEMBL21628804	0.93	PTGER4 (0.45)	PTGER4SMN1; SMN2PTGER2PPARGLTA4H
	SCHEMBL21628486	0.89	SMN1; SMN2 (0.40)	PTGER4SMN1; SMN2LTA4HKCNH2SCN9A
	SCHEMBL21628893	0.88	PTGER4 (0.45)	PTGER4SMN1; SMN2PTGER2PPARGLTA4H
	SCHEMBL21628645	0.87	SMN1; SMN2 (0.47)	PTGER4SMN1; SMN2SCN9AMRGPRX4LMNA
	SCHEMBL21628419	0.87	HDAC6 (0.42)	PTGER4
	SCHEMBL21628605	0.87	LMNA (0.47)	PTGER4SMN1; SMN2MRGPRX4LMNA
	SCHEMBL21628547	0.86	HPGD (0.43)	PTGER4SMN1; SMN2SCN9ALMNA
	SCHEMBL21628834	0.86	SMN1; SMN2 (0.40)	PTGER4SMN1; SMN2SCN9ALMNA
	SCHEMBL21628610	0.86	SMN1; SMN2 (0.39)	PTGER4SMN1; SMN2LTA4HKCNH2SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.