SCHEMBL21628784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628435	1.00	SCN9A (0.45)	SCN9AHRH3STAT3NAMPTDEGS1
	SCHEMBL21628704	0.99	SCN9A (0.45)	SCN9AHRH3STAT3NAMPTDEGS1
	SCHEMBL21656946	0.97	SCN9A (0.43)	SCN9AHRH3STAT3NAMPTHPGDS
	SCHEMBL21628762	0.94	CSF1R (0.43)	SCN9AHRH3HPGDSCSF1RHPGD
	SCHEMBL20482263	0.90	HDAC6 (0.51)	STAT3NAMPTDEGS1HPGDSHAO1
	SCHEMBL21628663	0.90	HDAC6 (0.51)	STAT3NAMPTDEGS1HPGDSHAO1
	SCHEMBL21628739	0.89	HDAC6 (0.52)	STAT3NAMPTDEGS1HAO1HDAC1
	SCHEMBL21628488	0.88	SMN1; SMN2 (0.42)	STAT3NAMPTDEGS1HPGDSHTT
	SCHEMBL21628383	0.88	SMN1; SMN2 (0.42)	STAT3NAMPTDEGS1HPGDSHTT
	SCHEMBL21628889	0.86	KMT2A (0.45)	STAT3NAMPTDEGS1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.