SCHEMBL21628800

SCHEMBL21628800

CC(C)c1ccc(Oc2ncc(C(=O)O)cc2F)cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 15/20 0.51
PTGER2 P43116 3/20 0.51
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
LTA4H P09960 2/20 0.41
KCNH2 Q12809 1/20 0.41
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29920978 0.88 ICAM1 (0.44) PTGER4PTGER2LTA4HKCNH2
SCHEMBL21628836 0.88 ICAM1 (0.44) PTGER4PTGER2LTA4HKCNH2
SCHEMBL21628555 0.87 PTGER4 (0.44) PTGER4PTGER2LTA4HKCNH2
SCHEMBL21628417 0.86 PTGER4 (0.51) PTGER4PTGER2LTA4HKCNH2PPARG
SCHEMBL21628727 0.86 PTGER4 (0.46) PTGER4PTGER2
SCHEMBL21628630 0.86 HDAC6 (0.49) PTGER4PTGER2
SCHEMBL21628731 0.86 HPGD (0.43) PTGER4PTGER2LTA4HKCNH2
SCHEMBL21628864 0.85 PTGER4 (0.47) PTGER4PTGER2PPARG
SCHEMBL21628780 0.85 PTGER4 (0.44) PTGER4PTGER2LTA4HKCNH2PPARG
SCHEMBL21628788 0.84 S1PR1 (0.48) PTGER4PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-12-21 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2022-11-03 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PTGER4 4387/4885PTGER2 4323/4885RXRA 684/4885
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PTGER4 4387/4885PTGER2 4323/4885RXRA 684/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK PTGER4 4252/4885PTGER2 4166/4885RXRA 709/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PTGER4 4387/4885PTGER2 4323/4885RXRA 684/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR PTGER4 3926/4885PTGER2 3679/4885RXRA 670/4885
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PTGER4 4387/4885PTGER2 4323/4885RXRA 684/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PTGER4 4387/4885PTGER2 4323/4885RXRA 684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.