SCHEMBL21628555

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628800	0.87	PTGER4 (0.51)	PTGER4PTGER2LTA4HKCNH2
	SCHEMBL21628788	0.87	S1PR1 (0.48)	PTGER4PTGER2NPBWR1RAB9ALMNA
	SCHEMBL21656919	0.87	LMNA (0.43)	PTGER4PTGER2LMNAMAPK1KMT2A
	SCHEMBL21628592	0.87	PTGER4 (0.45)	PTGER4PTGER2LMNAMAPTMAPK1
	SCHEMBL21628630	0.86	HDAC6 (0.49)	PTGER4PTGER2SCN9A
	SCHEMBL21628727	0.86	PTGER4 (0.46)	PTGER4PTGER2SCN9A
	SCHEMBL21628836	0.86	ICAM1 (0.44)	PTGER4PTGER2ALDH1A1KMT2ALTA4H
	SCHEMBL29920978	0.86	ICAM1 (0.44)	PTGER4PTGER2ALDH1A1KMT2ALTA4H
	SCHEMBL21628625	0.86	TDP1 (0.46)	PTGER4LMNAMAPTMAPK1ALDH1A1
	SCHEMBL21628731	0.84	HPGD (0.43)	PTGER4PTGER2RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.