SCHEMBL21628837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628857	0.97	PLK1 (0.49)	PLK1OPRM1OPRD1PLA2G4ATRPV1
	SCHEMBL29921175	0.97	PLK1 (0.49)	PLK1OPRM1OPRD1PLA2G4ATRPV1
	SCHEMBL21628698	0.96	PLK1 (0.48)	PLK1OPRM1OPRD1PLA2G4ATRPV1
	SCHEMBL21628686	0.93	PLK1 (0.51)	PLK1OPRM1OPRD1SMN1; SMN2ALDH1A1
	SCHEMBL21628665	0.91	SMPD1 (0.47)	PLK1TRPV1SMN1; SMN2NPC1ALDH1A1
	SCHEMBL21656917	0.89	PLK1 (0.49)	PLK1OPRM1OPRD1SMN1; SMN2HPGDS
	SCHEMBL21628883	0.88	SMPD1 (0.52)	TRPV1PTGER4
	SCHEMBL21628713	0.88	MDH1 (0.48)	PLK1TRPV1SMN1; SMN2NPC1ALDH1A1
	SCHEMBL21628425	0.87	RARB (0.48)	PLA2G4ASMN1; SMN2NPC1ALDH1A1NFKB1
	SCHEMBL21628415	0.87	SMPD1 (0.53)	PLK1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.