SCHEMBL2163149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17274059	0.79	HSD11B1 (0.42)	HSD11B1ALDH3A1NOD1CYP2D6GAA
	SCHEMBL22633460	0.78	HSD11B1 (0.41)	HSD11B1ALDH3A1NOD1CYP2D6GAA
	SCHEMBL22633446	0.78	HSD11B1 (0.41)	HSD11B1ALDH3A1NOD1CYP2D6GAA
	SCHEMBL2163839	0.74	MAPK8 (0.36)	HSD11B1CYP1A2LMNASMN1; SMN2KDM4E
	SCHEMBL18053572	0.73	POLB (0.43)	GAAHTTALDH1A1NPSR1KDM4E
	SCHEMBL2162698	0.73	CYP24A1 (0.40)	HSD11B1ALDH3A1NOD1GAACXCL8
	SCHEMBL23048328	0.72	SMPD3 (0.41)	GAAALDH1A1HPGDHSD17B10NPSR1
	SCHEMBL12324150	0.72	POLB (0.40)	GAAALDH1A1HPGDHSD17B10NPSR1
	SCHEMBL2162691	0.72	ALDH1A1 (0.40)	GAAALDH1A1HPGDHSD17B10NPSR1
	SCHEMBL25801350	0.72	SMPD3 (0.41)	GAAALDH1A1HPGDHSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.