SCHEMBL2163185

SCHEMBL2163185

Nc1cccc(Cn2cnnn2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
JAK2 O60674 1/20 0.41
CYP19A1 P11511 1/20 0.41
HMOX1 P09601 1/20 0.40
HTR1A P08908 1/20 0.40
HTR2C P28335 1/20 0.40
ALDH1A1 P00352 3/20 0.39
ABHD6 Q9BV23 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9872854 0.84 MAOA (0.47) CYP11B1CYP11B2MEN1KMT2AMAOA
SCHEMBL29788851 0.80 L3MBTL1 (0.53) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL31422371 0.80 KDM4E (0.50) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL29788847 0.80 KDM4E (0.50) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL10965028 0.80 KDM4E (0.50) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL4833617 0.79 MEN1 (0.53) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL2532477 0.78 CYP19A1 (0.55) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL5822531 0.77 JAK2 (0.53) L3MBTL1KDM4EMAPK1MEN1KMT2A
SCHEMBL9978689 0.77 CYP19A1 (0.53) L3MBTL1CYP11B1CYP11B2KDM4EMAPK1
SCHEMBL6479494 0.77 CYP19A1 (0.64) L3MBTL1CYP11B1CYP11B2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420300-B2 Method of producing multilayer printed wiring board and photosensitive dry film used therefor IBIDEN CO., LTD. (JP) 2013-04-16 US claimed
US-8420300-B2 Method of producing multilayer printed wiring board and photosensitive dry film used therefor IBIDEN CO., LTD. (JP) 2013-04-16 US disclosed
US-8356404-B2 Method of producing multilayer printed wiring board and photosensitive dry film used therefor IBIDEN CO., LTD. (JP) 2013-01-22 US disclosed
US-20110183267-A1 METHOD OF PRODUCING MULTILAYER PRINTED WIRING BOARD AND PHOTOSENSITIVE DRY FILM USED THEREFOR IBIDEN CO., LTD. (JP) 2011-07-28 US disclosed
US-20070095466-A1 Method of producing multilayer printed wiring board and photosensitive dry film used therefor IBIDEN CO., LTD. (JP) 2007-05-03 US disclosed
EP-1723132-A1 EP2 RECEPTOR AGONISTS ASTERAND UK LIMITED (GB) 2006-11-22 EP disclosed
WO-2005080367-A1 EP2 RECEPTOR AGONISTS PHARMAGENE LABORATORIES LIMITED (GB) 2005-09-01 WO disclosed