Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163185 | 0.84 | L3MBTL1 (0.50) | MAOAMAOBCYP19A1MEN1ALDH1A1 | |
| SCHEMBL6880513 | 0.80 | MEN1 (0.52) | MAOAMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL27706311 | 0.80 | HMOX1 (0.59) | MEN1ALDH1A1KMT2AHMOX1HRH3 | |
| SCHEMBL29436994 | 0.71 | MAOB (0.86) | MAOAMAOBCYP19A1ALDH1A1SIGMAR1 | |
| SCHEMBL2154372 | 0.71 | MAOB (0.86) | MAOAMAOBCYP19A1ALDH1A1SIGMAR1 | |
| SCHEMBL29788842 | 0.70 | RAB9A (0.52) | MAOACYP19A1MEN1ALDH1A1KMT2A | |
| SCHEMBL28179532 | 0.70 | MEN1 (0.52) | MEN1ALDH1A1KMT2AHMOX1HRH3 | |
| SCHEMBL6880509 | 0.70 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2AHMOX1HRH3 | |
| SCHEMBL29788848 | 0.70 | HMOX1 (0.56) | MEN1ALDH1A1KMT2ASIGMAR1HMOX1 | |
| SCHEMBL10555599 | 0.69 | MAOB (0.57) | MAOAMAOBCYP19A1SIGMAR1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |