Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 12/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21632518 | 0.77 | MERTK (0.32) | MERTK | |
| SCHEMBL22013966 | 0.76 | MAPT (0.35) | MAPTNPC1PTGDR2 | |
| SCHEMBL30908099 | 0.76 | MAPT (0.35) | MAPTNPC1PTGDR2 | |
| SCHEMBL26720538 | 0.76 | KMT2A (0.34) | MAPTNPC1 | |
| SCHEMBL21632555 | 0.75 | GPR119 (0.38) | MERTK | |
| SCHEMBL17837901 | 0.74 | DGAT1 (0.32) | MAPT | |
| SCHEMBL29514120 | 0.74 | DGAT1 (0.32) | MAPT | |
| SCHEMBL25226076 | 0.72 | NTRK1 (0.33) | — | |
| SCHEMBL17844432 | 0.70 | TRPV1 (0.33) | SMN1; SMN2 | |
| SCHEMBL17837491 | 0.68 | GRM1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023393-A1 | KINASE ANTAGONISTS AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS, INC. (US) | 2020-01-30 | — | — | WO | disclosed |
| WO-2020023393-A1 | KINASE ANTAGONISTS AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS, INC. (US) | 2020-01-30 | — | — | WO | disclosed |