Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520132 | 0.85 | PKM (0.67) | PKMGAARAB9ANPC1LMNA | |
| SCHEMBL2146952 | 0.84 | PKM (0.69) | PKMGAARAB9ANPC1LMNA | |
| SCHEMBL5275956 | 0.83 | MEN1 (0.68) | RAB9ALMNAPOLBNPSR1MAPT | |
| SCHEMBL17654496 | 0.80 | TP53 (0.61) | PKMGAARAB9ANPC1LMNA | |
| SCHEMBL6527375 | 0.79 | TP53 (0.66) | PKMGAARAB9ANPC1LMNA | |
| SCHEMBL9262989 | 0.78 | TLR8 (0.60) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2952525 | 0.78 | PKM (0.58) | PKMGAARAB9ANPC1LMNA | |
| SCHEMBL1668107 | 0.78 | KDM4E (0.64) | PKMGAARAB9ALMNAKDM4E | |
| SCHEMBL4077904 | 0.78 | LMNA (0.60) | PKMGAARAB9ANPC1LMNA | |
| SCHEMBL10415288 | 0.78 | LMNA (0.60) | PKMGAARAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017213809-A1 | NON-LINEAR SIDE CHAIN LIQUID CRYSTAL POLYORGANOSILOXANES AND METHODS FOR THEIR PREPARATION AND USE IN ELECTRO-OPTIC APPLICATIONS AND DEVICES | DOW CORNING CORPORATION (US) | 2017-12-14 | — | — | WO | disclosed |
| WO-2011081567-A1 | AGENT FOR TREATING MULTIPLE SCLEROSIS | АВЕРИН, Константин Михайлович (RU) | 2011-07-07 | — | — | WO | disclosed |