SCHEMBL2952525

SCHEMBL2952525

C=CCn1c(Cc2ccc(Cl)cc2)nc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.58
GAA P10253 2/20 0.58
LMNA P02545 5/20 0.57
DRD2 P14416 1/20 0.55
TBXA2R P21731 1/20 0.55
MEN1 O00255 2/20 0.53
TP53 P04637 2/20 0.53
MAPT P10636 2/20 0.53
KMT2A Q03164 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HTT P42858 1/20 0.53
RAB9A P51151 2/20 0.51
TNF P01375 1/20 0.51
CXCL8 P10145 1/20 0.51
SOS1 Q07889 1/20 0.51
NOD2 Q9HC29 1/20 0.51
NOD1 Q9Y239 1/20 0.51
GALR3 O60755 1/20 0.51
NR2F2 P24468 1/20 0.51
CYP1A2 P05177 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28238574 0.89 LMNA (0.68) PKMGAALMNAMEN1TP53
SCHEMBL8022214 0.84 LMNA (0.79) PKMLMNADRD2TBXA2RMEN1
SCHEMBL13187013 0.82 LMNA (0.85) PKMGAALMNADRD2TBXA2R
SCHEMBL1604271 0.79 LMNA (0.60) PKMGAALMNAMEN1TP53
SCHEMBL2901910 0.78 DRD2 (0.70) PKMGAADRD2TBXA2RMEN1
SCHEMBL2163308 0.78 PKM (0.68) PKMGAALMNAMEN1TP53
SCHEMBL29077099 0.78 KDM4E (0.77) GAALMNADRD2TBXA2RMEN1
SCHEMBL1520132 0.77 PKM (0.67) PKMGAALMNAMEN1TP53
SCHEMBL2146952 0.76 PKM (0.69) PKMGAALMNAMEN1TP53
SCHEMBL22080090 0.74 TP53 (0.66) LMNAMEN1TP53MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1886759-B1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEM (JP) 2016-10-05 EP disclosed
US-7754105-B2 Water-soluble preflux and usage of the same SHIKOKU CHEMICALS CORPORATION (JP) 2010-07-13 US disclosed
US-20080318070-A1 Water-Soluble Preflux and Usage of the Same SHIKOKU CHEMICALS CORPORATION (JP) 2008-12-25 US disclosed
EP-1886759-A1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2008-02-13 EP disclosed