Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782254 | 0.94 | CHRNB2 (0.58) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL755802 | 0.90 | CHRNB2 (0.51) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL10479366 | 0.88 | DRD2 (0.63) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL11019942 | 0.87 | DRD2 (0.55) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL23975528 | 0.82 | CHRNB2 (0.53) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL29548398 | 0.82 | APP (0.71) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL384725 | 0.82 | APP (0.71) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL3420663 | 0.82 | CHRNB2 (0.56) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL16902835 | 0.81 | APP (0.51) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL1470185 | 0.80 | CHRNB2 (0.69) | DRD2DRD4ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022785-A1 | NOVEL AUTOPHAGY-TARGETING CHIMERA (AUTOTAC) COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING DISEASES THROUGH TARGET PROTEIN DEGRADATION COMPRISING SAME | 주식회사 프로텍바이오 | 2020-01-30 | — | — | WO | disclosed |