Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245760 | 0.86 | MAOB (0.43) | MAOBNR4A2 | |
| SCHEMBL21634013 | 0.83 | KMT2A (0.48) | ALOX5MAOBL3MBTL1KMT2ARAB9A | |
| SCHEMBL21634014 | 0.83 | KMT2A (0.48) | ALOX5MAOBL3MBTL1KMT2ARAB9A | |
| SCHEMBL13412635 | 0.82 | ALOX5 (0.63) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL21634068 | 0.80 | ABCB1 (0.49) | MAOBMAPTMAPK1KMT2ARAB9A | |
| SCHEMBL4360097 | 0.80 | ALOX5 (0.46) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL11757028 | 0.78 | ADRB2 (0.55) | MAPTMAPK1TDP1KMT2ARAB9A | |
| SCHEMBL21634023 | 0.78 | ADRB2 (0.63) | PTGS1SLC6A2 | |
| SCHEMBL29721075 | 0.78 | ADRB2 (0.63) | PTGS1SLC6A2 | |
| SCHEMBL29742209 | 0.78 | ADRB2 (0.63) | PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022783-A9 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, ALLEVIATING, OR TREATING PROTEIN ABNORMALITY DISORDERS | 주식회사 프로텍바이오 | 2020-03-19 | — | — | WO | disclosed |
| WO-2020022783-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, ALLEVIATING, OR TREATING PROTEIN ABNORMALITY DISORDERS | 주식회사 프로텍바이오 | 2020-01-30 | — | — | WO | disclosed |
| WO-2020022784-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | 주식회사 프로텍바이오 | 2020-01-30 | — | — | WO | disclosed |