Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21634013 | 1.00 | KMT2A (0.48) | KMT2ASMN1; SMN2TSHRRAB9AHSD17B10 | |
| SCHEMBL25290710 | 0.86 | MAOB (0.47) | KMT2ASMN1; SMN2KCNH2MAOB | |
| SCHEMBL25290709 | 0.86 | MAOB (0.47) | KMT2ASMN1; SMN2KCNH2MAOB | |
| SCHEMBL10923979 | 0.85 | KCNH2 (0.58) | SMN1; SMN2TSHRKCNH2L3MBTL1ALOX15 | |
| SCHEMBL6075106 | 0.85 | RAB9A (0.59) | KMT2ASMN1; SMN2TSHRRAB9AHSD17B10 | |
| SCHEMBL6797677 | 0.85 | RAB9A (0.59) | KMT2ASMN1; SMN2TSHRRAB9AHSD17B10 | |
| SCHEMBL773087 | 0.84 | MAOB (0.59) | KMT2ASMN1; SMN2TSHRRAB9AHSD17B10 | |
| SCHEMBL21811960 | 0.84 | ADRB2 (0.53) | KMT2ASMN1; SMN2RAB9AABCB1 | |
| SCHEMBL21811961 | 0.84 | ADRB2 (0.53) | KMT2ASMN1; SMN2RAB9AABCB1 | |
| SCHEMBL10926521 | 0.84 | KMT2A (0.53) | KMT2ASMN1; SMN2TSHRRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828162-B1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES COMPRISING THE SAME | AUTOTAC INC (KR) | 2025-07-09 | — | — | EP | disclosed |
| US-11981618-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | AUTOTAC INC. (KR) | 2024-05-14 | — | — | US | disclosed |
| CN-112672993-B | Novel AUTOTAC chimeric compounds and compositions comprising same for preventing, ameliorating or treating diseases by targeted protein degradation | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| US-20210347749-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME | PROTECH CO., LTD. (KR) | 2021-11-11 | — | — | US | disclosed |
| EP-3828162-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, ALLEVIATING, OR TREATING PROTEIN ABNORMALITY DISORDERS | Protech Co., Ltd. (KR) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020022783-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, ALLEVIATING, OR TREATING PROTEIN ABNORMALITY DISORDERS | 주식회사 프로텍바이오 | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347749-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME | SQSTM1, ATG7, BECN1 | KMT2A 3635/4885SMN1; SMN2 327/4885TSHR 4433/4885 |
| US-11981618-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | SQSTM1, ATG7, BECN1 | KMT2A 3453/4885SMN1; SMN2 391/4885TSHR 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.